Endocrine Abstracts

Introduction: Although the effect of pre-admission insulin usage (PAIU) in diabetic COVID-19 patients remains uncertain, early studies have reported worse results in this group. Studies generally report in-hospital mortality rates. However, mortality also increases after discharge in COVID-19 patients; the effect of PAIU on this issue is unknown. This study was conducted to examine the effect of PAIU on COVID-19 diabetics’ 90-day mortality data, including the post-dischar...

Introduction and Aims: A higher prevalence of hyperglycemia has been reported in patients affected by coronavirus disease 2019 (COVID-19). Our study aims to retrospectively evaluate the course of hyperglycemia in patients recovering from COVID-19.Methods: All patients who were hospitalised in Çanakkale Onsekiz Mart University Hospital between March 2020 and March 2022 due to COVID-19 and whose HbA1c values were checked during hospitalisation were ex...

Background: In the presence of specific symptoms and signs, Cushing’s syndrome (CS) may be easily recognised. On the other hand, in overweight and obese patients without typical features of CS, diagnosis may be omitted. Our aim was to evaluate the prevalence of CS among overweight and obese patients.Methods: We enrolled 264 overweight and obese patients who has not overt CS clinical features between January 2012 and December 2014 at Ankara Numune Ed...

Association between idiopathic hypogonadotropic hypogonadism (IHH) and atherosclerotic disease in young males remains unclear. The present study aimed to determine the effect of improving the testosterone level on cardiovasculary (CV) risk markers in young males with IHH.Materials and methods: The study included 19 non-obese males with IHH and 17 healthy controls. The patients were treated with hCG therapy (n=8) or testosterone replacement (...

Introduction: Endogenous Cushing’s syndrome (CS) results from chronic excessive cortisol secretion. Discovering the source of disease is very important, but non-invasive tests cannot always be enough at the determination of correct location. We need more novel markers for distinguishing adrenal Cushing (AC) and pituitary Cushing (CD). We conducted this study for evaluating usefullness of preoperative DHEA-S levels at differentiating AC and CD.Materi...

Introduction: Hypogonadism have major affect on urogenital system also have several affect on other systems like cardiovascular and skeletal systems. There are very few study conducted on markers of atherosclerosis such as flow mediated dilatation (%FMD), carotis intima-media thickness(CIMT) and adipocytokine levels in idiopatic hypogonadotropic hypogonadal(IHH) males. The aim of this study was to evaluate this atherosclerotic risk factors in adult IHH male.<p class="abste...

Introduction: It’s well known that any form of diabetes insipidus (DI) can be exacerbated or first become appearent during pregnancy, since increased catabolism of ADH by plasental vasopressinas enzyme. Postpartum DI cases mostly presenting as a part of Sheean syndrome and began after postpartum first days. There was no any published case of isolated DI that began in the 6th month after deliveration in current literature.Case: A 37...

Introduction: There are two clinical types of amiodarone induced thyrotoxicosis (AIT). Type I AIT appears with hyperthyroidism and type II with a destructive thyrotoxicosis. Treatment of type I AIT includes antithyroid drugs meanwhile type II needs steroids as the first line therapy. If there is no respond to medical treatment, surgical approach must be considered. Here in we present a type II AIT case who had no respond to combined therapy therefore treated with surgical appr...

Purpose: To evaluate the relationship between basal dehydroepiandrosterone-sulfate (DHEA-S) levels and other tests used in the diagnosis and differential diagnosis of Cushing’s Syndrome (CS) among the patients with pathologically confirmed CS.Methods: In this multicenter study, the data of 623 patients with CS were evaluated retrospectively. The patients were classified as Group 1 (n = 353 Cushing’s disease;CD), Group 2 (n</e...

Introduction: Congenital adrenal hyperplasia (CAH) is a group of autosomal recessively inherited disorders that are characterised by inactivating mutations at various steps of adrenal steroidogenic pathways causing defective cortisol biosynthesis. 21-Hydroxylase enzyme deficiency (21-OHd) constitutes more than 95% of all CAH cases.Material & Methods: Medical records of patients with all forms of CAH from 19 adult endocrinology clinics located at six ...